MercyOne highlights critical differences in heart attack symptoms for women
February 18, 2026As part of American Heart Month, MercyOne is calling attention to the unique and often misunderstood symptoms of heart attacks in women, urging increased awareness and proactive heart health screenings.
Heart disease remains the leading cause of death for women. Their heart attack symptoms often differ from men’s and may appear mild or nonspecific. This subtle presentation can delay treatment and increase the risk of serious complications.
According to the American Heart Association, more than one in three women live with cardiovascular disease, and nearly half of women age 20 or older have some form of cardiovascular condition.
“Heart attack signs in women aren’t always the same as in men,” said Denise Sorrentino, MD, a cardiologist with MercyOne Iowa Heart Center. “Women often experience back, neck, and jaw pain instead of the classic chest pain men experience.”
They can also experience an overwhelming sense of fatigue and need to sit down and rest. Women may also suffer from nausea, abdominal pain and just feel poorly in general. Even though the signs may seem mild, the outcomes can be deadly if you don’t get help right away. “If you have any of these signs, call 911 or get to a hospital right away to get checked out,” said Sorrentino.
Women experiencing menopause are also at a higher risk of heart attacks since a drop in estrogen levels can contribute to inflammation and increased cholesterol buildup in the arteries.
Lifestyle factors continue to be the main driver of heart disease and heart attacks. Tobacco use, poor diet, physical inactivity and obesity account for a significant number of preventable deaths from heart disease.
MercyOne recommends proactive habits at any age, including:
- Eating a heart‑healthy diet
- Exercising regularly
- Quitting smoking
- Knowing your A1C, blood pressure, cholesterol and weight
- Understanding your family history
- Monitoring alcohol intake
- Taking prescribed medications as directed
- Managing stress
How healthy is your heart? Learn more by answering a few questions at https://www.mercyone.org/health-and-wellness/health-risk-assessments/heart-risk-assessment.